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Research sweep · deep · 2025 – 2026

Comparative LLM Usage Across Sectors

Comparative real-world usage of LLMs and adjacent AI technologies from June 2025 to June 2026: which models (GPT-5, Claude, Gemini, Llama, Mistral, DeepSeek, Qwen) dominate which sectors, how they are deployed (hosted API, Bedrock/Azure, self-hosted vLLM/Ollama, RAG, agents, fine-tuning), what workloads they serve, and how organisations measure, budget, and publicly report token cost and actual spend.

  • Claude Opus 4.8
  • financial
  • frontier
  • academic
  • vc
  • blogs
  • tech

Synthesised 2026-06-20

Narrative

The headline finding from Menlo Ventures' mid-2025 survey of 150 technical leaders is a market leadership reversal: enterprise LLM spend more than doubled from $3.5 billion in late 2024 to $8.4 billion by mid-2025, with Anthropic displacing OpenAI as the leading enterprise API provider. Menlo's year-end 2025 report refined the figures, estimating Anthropic holds 40% of enterprise LLM spend (up from 12% in 2023), while OpenAI fell from 50% to 27% over the same period. Google Gemini climbed to 21%, and the three firms together account for 88% of enterprise LLM API usage, leaving only 12% across Meta's Llama, Mistral, Cohere, and a long tail. Menlo's own portfolio investment in Anthropic is a declared conflict that tempers interpretation of these numbers, and the sample is self-selected among technically sophisticated teams.

McKinsey's State of AI 2025, published November 2025, provides a complementary and more sober read. Eighty-eight percent of respondents say their organisations use AI regularly across at least one function, up from 78% the year before, and 72% report using generative AI specifically, up from 33% in 2024. The scaling gap is the central finding: only about one-third of organisations report scaling AI enterprise-wide; two-thirds remain in what observers characterise as "pilot purgatory." Only 6% qualify as AI high performers attributing more than 5% of EBIT to AI, and just 39% report any enterprise-level financial impact. AI agents are the most prominent emerging deployment pattern, with roughly 62% of organisations at least experimenting and 23% scaling agentic systems. Adoption is highest in technology, media, telecommunications, and healthcare; financial services and legal are growing but face governance constraints. High performers are nearly three times more likely to be scaling agents and 2.8 times more likely to have fundamentally redesigned workflows.

A16z's survey of more than 100 CIOs, summarised in Kimberly Tan's "AI Adoption by the Numbers," shows enterprise LLM spend rising from $4.5 million to $7 million per organisation over two years, with CIOs projecting $11.6 million by end-2026. The report's standout structural finding is the death of the single-model regime: 81% of respondents now orchestrate three or more model families in production, up from 68% a year earlier, with frontier models reserved for high-stakes reasoning and smaller, cheaper alternatives handling routine workloads. AI budgets have migrated from innovation or R&D lines to core IT spend, growing at approximately 75% year-on-year, with innovation budget allocation dropping from 25% to just 7% of total AI spend. Separately, a16z payment data from over 200,000 startups (June to August 2025) confirmed that LLM assistants from OpenAI and Anthropic are the most-purchased AI applications among early-stage companies, with spend driven by multi-workflow ROI rather than point-solution capability.

Sequoia Capital's AI Ascent 2026, held in April 2026, declared the agent era the defining frame of the year. Sonya Huang argued that 2022 to 2024 was the chat interface phase, 2024 to 2025 the reasoning model phase, and 2026 the phase in which systems pursue goals rather than respond to prompts. Pat Grady identified a widening "diffusion gap" between what frontier labs ship and what Fortune 500 firms have deployed, framing the application layer as the primary investment opportunity. Gartner's 2025 Hype Cycle for Artificial Intelligence placed generative AI in the Trough of Disillusionment, noting that organisations struggle to demonstrate tangible ROI and face governance, hallucination, and integration challenges, while projecting that AI agents and AI-ready data are the two fastest-advancing technologies on the curve. CB Insights mapped more than 400 AI agent startups across 16 categories and identified coding AI agent revenue scaling fast in 2025, with big tech and leading LLM developers expected to own general-purpose agents while smaller players compete on vertical specificity. Open-weight models including Llama 4, Qwen 3, and DeepSeek R1 have reached performance parity with closed frontier models on most published benchmarks by 2026, but Menlo's production data shows closed-source models still controlling roughly 87% to 88% of observed enterprise API usage, with open-weight adoption strongest in self-hosted code generation and compliance-sensitive sectors where data residency matters.


Sources

ID Title Outlet Date Significance
v1 2025 Mid-Year LLM Market Update: Foundation Model Landscape + Economics Menlo Ventures 2025-07 Primary quantitative source on enterprise LLM market share and spend as of mid-2025, showing Anthropic displacing OpenAI and total enterprise LLM spend reaching $8.4 billion.
v2 2025: The State of Generative AI in the Enterprise Menlo Ventures 2025-12 Year-end enterprise survey estimating Anthropic at 40% of enterprise LLM spend, OpenAI at 27%, Google at 21%, and three firms together at 88% of API usage, with code generation as the breakout use case.
v3 Enterprise LLM Spend Reaches $8.4B as Anthropic Overtakes OpenAI Globe Newswire / Menlo Ventures 2025-07 Official press release anchoring the mid-2025 Menlo Ventures market share figures, including Meta Llama at 9% and DeepSeek at 1% of API usage.
v4 The state of AI in 2025: Agents, innovation, and transformation McKinsey Global Institute / QuantumBlack 2025-11 Definitive large-scale global survey showing 88% AI adoption, only 6% high performers, agent deployment by sector, and the enterprise scaling gap as the central structural challenge.
v5 AI in 2025: Building Blocks Firmly in Place Sequoia Capital 2024-12 Sequoia's annual prediction report identifying the five finalist frontier lab players and framing AI search and code generation as the leading near-term use cases.
v6 AI Ascent 2026 Sequoia Capital 2026-05 Conference summary declaring 2026 the year of agents, identifying the diffusion gap between frontier capability and Fortune 500 deployment, and framing the application layer as the primary VC opportunity.
v7 Insights from AI Ascent 2025 Sequoia Capital 2025-05 Documents Sequoia's 2025 conference emphasis on open-source model preservation, Ollama and OpenRouter deployment patterns, and reasoning models catalysing enterprise adoption.
v8 Gartner Hype Cycle Identifies Top AI Innovations in 2025 Gartner 2025-08 Official Gartner Hype Cycle placing AI agents and AI-ready data as the fastest-advancing technologies, providing the canonical technology maturity framing for enterprise AI planning.
v9 Gartner Hype Cycle Highlights Rise in Gen AI and Automation for Legal, Risk, and Compliance Gartner 2025-09 Sector-specific Gartner analysis warning that legal and compliance functions risk disillusionment if AI is adopted before foundational technology (contract lifecycle management, privacy tools) is in place.
v10 A16Z Report: Startup Spend Confirms LLMs Central to Applications MLQ.ai / a16z 2025-09 Covers a16z's payment-data analysis of 200,000+ startups from June to August 2025, showing OpenAI and Anthropic as the most-purchased AI applications and confirming spend driven by multi-workflow ROI.
v11 Scoping the Enterprise LLM Market Andreessen Horowitz (a16z) 2024-04 A16z foundational framing of enterprise LLM architecture decisions, transformer standardisation, and hardware competition, providing context for subsequent investment theses.
v12 State of AI Q3 2025 Report CB Insights 2025-11 Documents Q3 2025 funding rounds including Anthropic ($13B Series F), OpenAI ($8.3B), and Mistral AI ($1.5B Series C), anchoring the capital concentration in closed frontier model developers.
v13 The AI agent market map: March 2025 edition CB Insights 2026-03 Maps 400+ AI agent startups across 16 categories, projects big tech dominance in general-purpose agents, and identifies AI-native workspaces as the emerging form factor beyond copilots.
v14 CB Insights: The Year of AI Agents CB Insights 2025-12 Annual synthesis identifying 500+ AI agent startups founded since 2023, covering coding agent revenue scaling, the AI agent tech stack across 135+ companies, and market size projections for the $5B+ enterprise agent category.
v15 Deep Dive: AI Adoption in the Enterprise (a16z CIO survey synthesis) Substack / Michael Burnett 2026-04 Synthesises a16z's Kimberly Tan CIO survey data showing enterprise LLM spend rising from $4.5M to $7M, 81% of enterprises orchestrating three or more model families, and the shift to core IT budget classification.
v16 Enterprise LLM Market Global Market Analysis Report Future Market Insights 2026-04 Market sizing report projecting enterprise LLM market from $5.9B in 2025 to $91.5B by 2036 at 28.3% CAGR, with cloud-based deployment leading at 59% of organisational choices.
v17 McKinsey State of AI 2025: 12 Key Findings Every Leader Should Know Gend.co 2025-12 Detailed breakdown of McKinsey's 2025 findings including the scaling bottleneck, regulated sector constraints, and the finding that workflow redesign rather than model choice drives high-performer advantage.
v18 Sequoia AI Ascent 2026: The future of AI (Sonya Huang breakdown) The AI Opportunities / Sequoia Capital 2026-05 Detailed narrative of Sequoia's agent-era thesis, the $10 trillion services addressable market framing, and the diffusion gap between model capability and Fortune 500 deployment pace.
v19 Sequoia Ascent 2026 summary (Andrej Karpathy) Andrej Karpathy / Sequoia Capital 2026-04 Karpathy's first-hand account of the Software 3.0 thesis presented at Sequoia AI Ascent 2026, framing the context window as the new programming surface and agent orchestration as the dominant engineering paradigm.
v20 Private LLM Growth Expected as Enterprises Shift GenAI to Secure Domain-Specific Systems MarketersMEdia / Financial Content 2026-01 Covers Gartner and IDC projections on private LLM adoption, citing $2.52 trillion in worldwide AI spending by 2026 and $370 billion in cumulative generative AI implementation spend from 2024 to 2027.
v21 Evolving LLM Market: Anthropic Leads 2025 Enterprise Share AI CERTs 2025-12 Critical analysis of the Menlo Ventures methodology noting the firm's investment in Anthropic as a conflict of interest and flagging that closed-source models controlled approximately 87% of observed enterprise usage.
v22 State of AI 2025: 78% Adoption, 74% ROI, but Only 6% Scale Punku.ai 2025-11 Cross-references McKinsey, Google Cloud, and Gartner data showing 23% of organisations scaling AI agents, Google Cloud finding 74% first-year ROI, and Gartner data on AI project durability by organisational maturity.
v23 Menlo Ventures: Enterprise LLM Spend Reaches $8.4B (HPCwire report) HPCwire / AIwire 2025-08 Trade press coverage anchoring the mid-2025 Menlo data and noting that inference has overtaken training as the primary driver of enterprise LLM spend.
v24 Gartner Hype Cycle for AI 2025 (Hyland analysis) Hyland / Gartner 2025-06 Access point for the June 2025 Gartner Hype Cycle for Artificial Intelligence, authored by Haritha Khandabattu and Birgi Tamersoy, identifying AI-ready data and edge AI as near-term mainstream candidates.
v25 OpenAI vs Anthropic: Ramp Data Shows 36% vs 12% Penetration SaaStr / Ramp 2025-12 Ramp payment data from billions in managed spend shows OpenAI at 36.5% and Anthropic at 12.1% of business wallet adoption, a different distribution from Menlo's API production share, illustrating the importance of data source methodology.

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